Anyone who is trying to lose weight or generally enhance weight management. People on low-carb, paleo or Keto diets. Individuals who are restricting sugar intake, particularly those with diabetes or at risk of developing Type 2 diabetes. People who suffer frequent gastric distress, including diarrhea, constipation, irritable bowel syndrome, cramping, etc. People whose lives do not enable them to receive adequate exposure to sunlight and therefore need additional vitamin D3. People on vegetarian diets or do not eat much seafood often need incremental vitamin B12